Air Purifier Ranking

Best Large (250–399 CADR) Air Purifiers

Open living areas up to about 600 sq ft. 17 ranked by overall score. Updated October 18, 2026.

1

Dreo Macro Pro 4.1

$130

#1 in Large (250–399 CADR) · 258 smoke CADR · ~400 sq ft · 53 dB max · 11.0 lb

Strong CADR per dollar with app and auto mode; very quiet on low.

$0.50 per CADR$100/yr filtersAHAM VerifideAuto modeEnergy Star Spec-based

Amazon Dreo Full review →

2

Blueair Blue Pure 311i Max 3.9

$170

#2 in Large (250–399 CADR) · 250 smoke CADR · ~388 sq ft · 50 dB max · 8.0 lb

Medium-room Blueair with very low power draw and app.

$0.68 per CADR$120/yr filtersAHAM VerifideAuto modeEnergy Star Spec-based

Amazon Blueair Full review →

3

Levoit Core 400S 3.8

$180

#3 in Large (250–399 CADR) · 260 smoke CADR · ~403 sq ft · 52 dB max · 14.0 lb

Very efficient CADR per watt; filters are rated for only six months.

$0.69 per CADR$100/yr filtersAHAM VerifideAuto modeEnergy Star Spec-based

Amazon Levoit Full review →

4

Blueair Blue Pure 311 Auto 3.7

$200

#4 in Large (250–399 CADR) · 250 smoke CADR · ~388 sq ft · 50 dB max · 8.0 lb

Efficient medium-room unit; superseded by the 311i Max.

$0.80 per CADR$120/yr filtersAHAM VerifideAuto modeEnergy Star Spec-based

Amazon Blueair Full review →

5

Coway Airmega 300 3.6

$279

#5 in Large (250–399 CADR) · 300 smoke CADR · ~465 sq ft · 52 dB max · 21.4 lb

Two-sided filtration with a real carbon layer; filters cost more than most.

$0.93 per CADR$110/yr filtersAHAM VerifideAuto mode1.1 lb carbonEnergy Star Spec-based

Amazon Coway Full review →

6

Coway Airmega 400 3.4

$379

#6 in Large (250–399 CADR) · 350 smoke CADR · ~542 sq ft · 52 dB max · 24.7 lb

High CADR at a quiet 52 dB maximum; annual filter cost is among the highest here.

$1.08 per CADR$130/yr filtersAHAM VerifideAuto mode1.3 lb carbonEnergy Star Spec-based

Amazon Coway Full review →

7

Coway Airmega 400S 3.4

$449

#7 in Large (250–399 CADR) · 350 smoke CADR · ~542 sq ft · 52 dB max · 24.7 lb

Airmega 400 with Wi-Fi app control.

$1.28 per CADR$130/yr filtersAHAM VerifideAuto mode1.3 lb carbonEnergy Star Spec-based

Amazon Coway Full review →

8

Levoit EverestAir 3.4

$400

#8 in Large (250–399 CADR) · 360 smoke CADR · ~558 sq ft · 52 dB max · 21.0 lb

Levoit's flagship with a laser sensor and directional vent; expensive for the CADR.

$1.11 per CADR$160/yr filtersAHAM VerifideAuto modeEnergy Star Spec-based

Amazon Levoit Full review →

9

Alen BreatheSmart 75i 3.4

$599

#9 in Large (250–399 CADR) · 347 smoke CADR · ~538 sq ft · 49 dB max · 27.0 lb

Quiet at full speed and well built; price per CADR is high.

$1.73 per CADR$99/yr filtersAHAM VerifideAuto modeEnergy Star Spec-based

Amazon Alen Full review →

10

Blueair Blue Pure 211+ 3.3

$250

#10 in Large (250–399 CADR) · 350 smoke CADR · ~542 sq ft · 56 dB max · 13.0 lb

High CADR, simple one-button operation, fabric prefilter; no auto mode and short filter life.

$0.71 per CADR$140/yr filtersAHAM VerifideEnergy Star Spec-based

Amazon Blueair Full review →

11

Blueair Blue Pure 211+ Auto 3.3

$280

#11 in Large (250–399 CADR) · 350 smoke CADR · ~542 sq ft · 56 dB max · 13.0 lb

211+ with a particle sensor and auto mode.

$0.80 per CADR$140/yr filtersAHAM VerifideAuto modeEnergy Star Spec-based

Amazon Blueair Full review →

12

Honeywell HPA5300 3.2

$250

#12 in Large (250–399 CADR) · 300 smoke CADR · ~465 sq ft · 58 dB max · 18.0 lb

HPA300 internals with a particle sensor, auto mode and app.

$0.83 per CADR$60/yr filtersAHAM VerifideAuto modeEnergy Star Spec-based

Amazon Honeywell Full review →

13

Honeywell HPA300 3.1

$190

#13 in Large (250–399 CADR) · 300 smoke CADR · ~465 sq ft · 60 dB max · 17.0 lb

Proven large-room CADR at a fair price; loud and power-hungry at full speed, no auto mode.

$0.63 per CADR$60/yr filtersAHAM VerifideEnergy Star Spec-based

Amazon Honeywell Full review →

14

Medify MA-40 3.0

$170

#14 in Large (250–399 CADR) · 330 smoke CADR · ~512 sq ft · 56 dB max · 15.0 lb

High claimed CADR for the money; not AHAM listed, and filters are short-lived.

$0.52 per CADR$160/yr filters Spec-based

Amazon Medify Full review →

15

Rabbit Air A3 3.0

$600

#15 in Large (250–399 CADR) · 262 smoke CADR · ~406 sq ft · 51 dB max · 20.0 lb

Rabbit Air's larger unit with app and a laser sensor; premium price.

$2.29 per CADR$100/yr filtersAHAM VerifideAuto modeEnergy Star Spec-based

Amazon Rabbit Air Full review →

16

Blueair HealthProtect 7470i 2.6

$550

#16 in Large (250–399 CADR) · 300 smoke CADR · ~465 sq ft · 51 dB max · 27.0 lb

Premium build and very quiet low speed; CADR per dollar is poor.

$1.83 per CADR$240/yr filtersAHAM VerifideAuto modeEnergy Star Spec-based

Amazon Blueair Full review →

17

Mila Air Purifier 2.6

$299

#17 in Large (250–399 CADR) · 263 smoke CADR · ~408 sq ft · 55 dB max · 18.0 lb

Sensor-heavy smart unit with swappable filter types; filters are expensive.

$1.14 per CADR$198/yr filtersAHAM VerifideAuto modeEnergy Star Spec-based

Amazon Mila Full review →

Compare the top picks

#	Model	Smoke CADR	Dust	Pollen	W	dB max	Filters/yr	$/CADR	Score
1	Dreo Macro Pro	258	260	258	40	53	$100	0.5	77
2	Blueair Blue Pure 311i Max	250	250	250	36	50	$120	0.7	71
3	Levoit Core 400S	260	242	250	38	52	$100	0.7	69
4	Blueair Blue Pure 311 Auto	250	250	250	30	50	$120	0.8	68
5	Coway Airmega 300	300	300	300	57	52	$110	0.9	64
6	Coway Airmega 400	350	350	350	66	52	$130	1.1	61
7	Coway Airmega 400S	350	350	350	66	52	$130	1.3	60
8	Levoit EverestAir	360	340	350	49	52	$160	1.1	60
9	Alen BreatheSmart 75i	347	350	350	60	49	$99	1.7	60
10	Blueair Blue Pure 211+	350	350	350	61	56	$140	0.7	57
11	Blueair Blue Pure 211+ Auto	350	350	350	61	56	$140	0.8	57
12	Honeywell HPA5300	300	320	300	120	58	$60	0.8	54
13	Honeywell HPA300	300	320	300	130	60	$60	0.6	53
14	Medify MA-40	330	330	330	68	56	$160	0.5	50
15	Rabbit Air A3	262	270	265	57	51	$100	2.3	50
16	Blueair HealthProtect 7470i	300	300	300	55	51	$240	1.8	41
17	Mila Air Purifier	263	270	265	55	55	$198	1.1	39